PITTSBURGH PIRATES TRANSACTIONS
| Date | Player | Pos | Move | Old Team | New Team | Notes |
|---|---|---|---|---|---|---|
| 4/8/22 | Quinn Priester | RHP | 7-Day IL | Altoona | Altoona | Oblique Injury |
| 4/8/22 | Jeffrey Passantino | RHP | 60-Day IL | Altoona | Altoona | |
| 4/8/22 | Aaron Shortridge | RHP | 7-Day IL | Altoona | Altoona | |
| 4/8/22 | Fabricio Macias | OF | 7-Day IL | Altoona | Altoona | |
| 4/7/22 | Jake Marisnick | OF | Signed | Free Agent | Pittsburgh | |
| 4/7/22 | Greg Allen | OF | 60-Day IL | Pittsburgh | Pittsburgh | |
| 4/7/22 | Adonis Medina | RHP | Traded | Pittsburgh | NY Mets | Cash Considerations |
| 4/6/22 | Andrew Knapp | C | Signed | Free Agent | Pittsburgh | |
| 4/6/22 | Adonis Medina | RHP | DFA | Indianapolis | DFA | |
| 4/6/22 | Trey McGough | LHP | 7-Day IL | Indianapolis | Indianapolis | Retro 4/5 |
| 4/5/22 | Taylor Davis | C | Transferred | Indianapolis | Altoona | |
| 4/5/22 | Michael Perez | C | Transferred | Indianapolis | Altoona | |
| 4/5/22 | Bligh Madris | OF | Transferred | Indianapolis | Altoona | |
| 4/5/22 | Joe Jacques | LHP | 60-Day IL | Indianapolis | Altoona | |
| 4/2/22 | Adonis Medina | RHP | Optioned | Pittsburgh | Indianapolis | |
| 4/1/22 | Josh VanMeter | 2B | Traded | Arizona | Pittsburgh | For RHP Listher Sosa |
| 4/1/22 | Jared Oliva | OF | DFA | Pittsburgh | DFA | |
| 4/1/22 | Ethan Paul | SS | Released | Pittsburgh | Free Agent | |
| 3/29/22 | Oneil Cruz | SS | Optioned | Pittsburgh | Indianapolis | |
| 3/27/22 | Roansy Contreras | RHP | Optioned | Pittsburgh | Indianapolis | |
| 3/27/22 | Rodolfo Castro | 2B | Optioned | Pittsburgh | Indianapolis | |
| 3/27/22 | Canaan Smith-Njigba | CF | Optioned | Pittsburgh | Indianapolis | |
| 3/27/22 | Jared Oliva | OF | Optioned | Pittsburgh | Indianapolis | |
| 3/24/22 | Jack Suwinski | OF | Optioned | Pittsburgh | Indianapolis | |
| 3/24/22 | Liover Peguero | SS | Optioned | Pittsburgh | Indianapolis | |
| 3/24/22 | Tucupita Marcano | SS | Optioned | Pittsburgh | Indianapolis | |
| 3/23/22 | Dylan Busby | INF | Released | Pittsburgh | Free Agent | |
| 3/23/22 | Alex Manasa | RHP | Released | Pittsburgh | Free Agent | |
| 3/23/22 | Jake Snider | OF | Released | Pittsburgh | Free Agent | |
| 3/22/22 | Travis Swaggerty | OF | Optioned | Pittsburgh | Indianapolis | |
| 3/21/22 | Eric Hanhold | RHP | Outrighted | Pittsburgh | Indianapolis | |
| 3/17/22 | Austin Brice | RHP | Signed | Free Agent | Pittsburgh | Minor League Deal |
| 3/17/22 | Chase De Jong | RHP | Signed | Free Agent | Pittsburgh | Minor League Deal |
| 3/17/22 | Eric Hanhold | RHP | DFA | Pittsburgh | DFA | |
| 3/16/22 | Adonis Medina | RHP | Claimed | Philadelphia | Pittsburgh | |
| 3/16/22 | Arlinthon De Dios | RHP | Released | Pittsburgh | Free Agent | |
| 3/16/22 | Wander Romero | RHP | Released | Pittsburgh | Free Agent | |
| 3/16/22 | Alex Roth | RHP | Released | Pittsburgh | Free Agent | |
| 3/16/22 | Cory Wood | INF | Released | Pittsburgh | Free Agent | |
| 3/16/22 | Francisco Quintero | INF | Released | Pittsburgh | Free Agent | |
| 3/16/22 | Eliazer Montero | INF | Released | Pittsburgh | Free Agent | |
| 3/15/22 | Daniel Vogelbach | 1B | Signed | Free Agent | Pittsburgh | |
| 3/15/22 | Heath Hembree | RHP | Signed | Free Agent | Pittsburgh | |
| 3/15/22 | Blake Cederlind | RHP | 60-Day IL | Pittsburgh | Pittsburgh | |
| 3/15/22 | Nick Mears | RHP | 60-Day IL | Pittsburgh | Pittsburgh | |
| 3/13/22 | Aaron Fletcher | LHP | Claimed | Seattle | Pittsburgh | |
| 3/11/22 | Taylor Davis | C | Signed | Free Agent | Pittsburgh | |
| 1/26/22 | Mariano Dotel | INF | Released | Pittsburgh | Free Agent | |
| 1/26/22 | Antonio Gonzalez | RHP | Released | Pittsburgh | Free Agent | |
| 1/26/22 | Francisco Hodge | LHP | Released | Pittsburgh | Free Agent | |
| 1/26/22 | Angel Suero | RHP | Released | Pittsburgh | Free Agent | |
| 1/24/22 | Wali Pierre | RHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Roinny Aguiar | SS | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Hader Blanco | LHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Tony Blanco Jr. | OF | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Angel Camacho | LHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Hung-Leng Chang | RHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Jarlen De La Paz | LHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Yordany De Los Santos | SS | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Daje Morales | SS | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Dermis Ordonez | RHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Christopher Orelin | SS | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Eduardo Oviedo | OF | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Isaac Paulino | SS | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Axiel Plaz | C | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Richard Ramirez | C | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Angel Rodriguez | OF | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Pitterson Rosa | RHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Alberto Saba | RHP | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Carlos Tirado | 1B | Signed | Free Agent | Pittsburgh | International FA |
| 1/15/22 | Alexis Torres | RHP | Signed | Free Agent | Pittsburgh | International FA |
